Brief Information of the Compound and Protein
Compound Name
(E,Z)-6-(2-((2-Oxo-5-thioxoimidazolidin-4-ylidene)methyl)quinolin-6-yl)-3,4-dihydroisoquinolin-1(2H)-one
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PubChem ID
CID: 76324713
Canonical SMILES
O=C1NC(=S)/C(=C/c2ccc3cc(-c4ccc5c(c4)CCNC5=O)ccc3n2)N1
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Compound Formula C22H16N4O2S
Compound Structure
Protein Name
Perforin-1
Protein Classification
Ion channel
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Other ion channel
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Pore-forming toxins (proteins and peptides)
Uniprot ID
P14222
Gene Name
PRF1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat Homo sapiens (Human)  1
1
IC50 = 2550 nM
   TI
   LI
   LO
   TS