Brief Information of the Compound and Protein
Compound Name
7-[5-[(E)-(5-oxo-2-sulfanylideneimidazolidin-4-ylidene)methyl]thiophen-2-yl]-3,4-dihydro-2H-isoquinolin-1-one
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PubChem ID
CID: 53259663
SID: 124400977
Canonical SMILES
O=C1NC(=S)N\C1=C\c1ccc(s1)-c1ccc2CCNC(=O)c2c1
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Compound Formula C17H13N3O2S2
Compound Structure
Protein Name
Perforin-1
Protein Classification
Ion channel
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Other ion channel
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Pore-forming toxins (proteins and peptides)
Uniprot ID
P14222
Gene Name
PRF1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat Homo sapiens (Human)  1
1
IC50 = 640 nM
   TI
   LI
   LO
   TS