Brief Information of the Compound and Protein
| Compound Name |
2-amino-6-halopurine analogue, 20
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PubChem ID | |||||
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Compound Structure |
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| Protein Name |
Heat shock protein HSP 90-alpha
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Protein Classification |
Other cytosolic protein
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| Uniprot ID | Gene Name | HSP90AA1 |
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Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000083 | MCF-7 | Homo sapiens (Human) | 1 |
| 1 |
EC50 = 38 nM
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TI
LI
LO
TS
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|---|---|---|---|
| CL000013 | Sf9 | Spodoptera frugiperda (Fall armyworm) | 1 |
| 1 |
Ki = 2 nM
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TI
LI
LO
TS
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Biochemical Assays
| 1 | IC50 = 5.1 nM | ||
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| 2 | IC50 = 19 nM | ||
| 3 | IC50 = 29 nM | ||
| 4 | IC50 = 52 nM | ||
| 5 | IC50 = 65.7 nM | ||
| 6 | Ki = 1.7 nM | ||