Brief Information of the Compound and Protein
Compound Name
N-cyclopropyl-N-(1-(4-(methylsulfonyl)-2-(trifluoromethyl)benzoyl)azetidin-3-yl)-3-(trifluoromethyl)benzenesulfonamide
    Show/Hide
PubChem ID
CID: 76331792
Canonical SMILES
CS(=O)(=O)c1ccc(C(=O)N2CC(N(C3CC3)S(=O)(=O)c3cccc(C(F)(F)F)c3)C2)c(C(F)(F)F)c1
    Show/Hide
Compound Formula C22H20F6N2O5S2
Compound Structure
Protein Name
Voltage-dependent N-type calcium channel subunit alpha-1B
Protein Classification
Ion channel
>
Voltage-gated ion channel
>
Voltage-gated calcium channel
Uniprot ID
Q00975
Gene Name
CACNA1B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 270 nM
   TI
   LI
   LO
   TS