Brief Information of the Compound and Protein
Compound Name
2-[(9R)-9-pyridin-2-yl-6-oxaspiro[4.5]decan-9-yl]-N-(thiophen-2-ylmethyl)ethanamine
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PubChem ID
CID: 72712370
Canonical SMILES
C(C[C@]1(CCOC2(CCCC2)C1)c1ccccn1)NCc1cccs1
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Compound Formula C21H28N2OS
Compound Structure
Protein Name
Kappa-type opioid receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Opioid receptor
Uniprot ID
P41145
Gene Name
OPRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 900 nM
   TI
   LI
   LO
   TS