Brief Information of the Compound and Protein
Compound Name
9-(4,6-dimethylpyrimidin-2-yl)-2-[(5-methoxy-1H-indol-3-yl)methyl]-2,9-diazaspiro[5.5]undecan-1-one
    Show/Hide
PubChem ID
CID: 72704097
Canonical SMILES
COc1ccc2[nH]cc(CN3CCCC4(CCN(CC4)c4nc(C)cc(C)n4)C3=O)c2c1
    Show/Hide
Compound Formula C25H31N5O2
Compound Structure
Protein Name
Orexin receptor type 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Orexin receptor
Uniprot ID
O43614
Gene Name
HCRTR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 0.166 nM
   TI
   LI
   LO
   TS