Brief Information of the Compound and Protein
Compound Name
2-(1H-indol-4-ylmethyl)-9-quinoxalin-2-yl-2,9-diazaspiro[5.5]undecan-1-one
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PubChem ID
CID: 53259112
SID: 124400449
Canonical SMILES
O=C1N(Cc2cccc3[nH]ccc23)CCCC11CCN(CC1)c1cnc2ccccc2n1
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Compound Formula C26H27N5O
Compound Structure
Protein Name
Orexin receptor type 2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43614
Gene Name
HCRTR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 77.62 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Kd = 130 nM
2 Ki = 63 nM