Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US8530648, 6
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 PubChem ID
CID: 53259279
SID: 124400608
Canonical SMILES
O=C1N(Cc2ccccc2)CCCC11CCN(CC1)c1cnc2ccccc2n1
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Compound Formula C24H26N4O
Compound Structure
Protein Name
 Protein Info 
Orexin receptor type 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Orexin receptor
Uniprot ID
O43614
Gene Name
HCRTR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 181.97 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Kd = 300 nM
2 Ki = 371 nM