Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US8530648, 85
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 PubChem ID
CID: 53259634
SID: 124400948
Canonical SMILES
Cc1ccc(C)c(CN2C(=O)CCCC22CCN(CC2)c2cnc3ccccc3n2)c1
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Compound Formula C26H30N4O
Compound Structure
Protein Name
 Protein Info 
Orexin receptor type 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43614
Gene Name
HCRTR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 12.88 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Kd = 36 nM
2 Ki = 16 nM