Brief Information of the Compound and Protein
Compound Name
5-((3-fluorophenyl)ethynyl)-N-neopentylpicolinamide
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PubChem ID
CID: 70896663
Canonical SMILES
CC(C)(C)CNC(=O)c1ccc(C#Cc2cccc(F)c2)cn1
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Compound Formula C19H19FN2O
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P31424
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 16.6 nM
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