Brief Information of the Compound and Protein
Compound Name
6-[[6-(3,4-difluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl]quinoline
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PubChem ID
CID: 24965874
SID: 56263997
Canonical SMILES
Fc1ccc(cc1F)-c1ccc2nnc(Cc3ccc4ncccc4c3)n2n1
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Compound Formula C21H13F2N5
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  1
1
IC50 = 48 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 44 nM