Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[[6-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl]phenol
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 PubChem ID
CID: 57691336
Canonical SMILES
Oc1ccc(Cc2nnc3ccc(nn23)-c2ccc(F)cc2)cc1
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Compound Formula C18H13FN4O
Compound Structure
Protein Name
 Protein Info 
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1310 nM
   TI
   LI
   LO
   TS
CL000267 SNU-5
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 380 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 200 nM
2 Ki = 316 nM