Brief Information of the Compound and Protein
Compound Name
6-[(1S)-1-[5-(1-methylpyrazol-4-yl)triazolo[4,5-b]pyrazin-3-yl]ethyl]quinoline
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PubChem ID
CID: 59341847
Canonical SMILES
C[C@@H](c1ccc2ncccc2c1)n1nnc2ncc(nc12)-c1cnn(C)c1
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Compound Formula C19H16N8
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  1
1
IC50 = 0.7 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 1.4 nM