Brief Information of the Compound and Protein
Compound Name
3-[3-(quinolin-6-ylmethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]benzonitrile
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PubChem ID
CID: 24964818
SID: 56262949
Canonical SMILES
N#Cc1cccc(c1)-c1ccc2nnc(Cc3ccc4ncccc4c3)n2n1
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Compound Formula C22H14N6
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
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Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  1
1
IC50 = 19 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 13 nM