Brief Information of the Compound and Protein
Compound Name
4-[3-[(1S)-1-(1H-pyrrolo[2,3-b]pyridin-3-yl)ethyl]-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]benzonitrile
    Show/Hide
PubChem ID
CID: 24871946
SID: 50127015
Canonical SMILES
C[C@@H](c1c[nH]c2ncccc12)c1nnc2ccc(nn12)-c1ccc(cc1)C#N
    Show/Hide
Compound Formula C21H15N7
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  1
1
IC50 = 23 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 14.9 nM