Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2,2-dimethyl-3-phenyl-3-(1-propan-2-ylindazol-5-yl)-N-(1,3,4-thiadiazol-2-yl)propanamide
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 PubChem ID
CID: 59252869
Canonical SMILES
CC(C)n1ncc2cc(ccc12)C(c1ccccc1)C(C)(C)C(=O)Nc1nncs1
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Compound Formula C23H25N5OS
Compound Structure
Protein Name
 Protein Info 
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 195 nM
   TI
   LI
   LO
   TS
2
EC50 = 301 nM
   TI
   LI
   LO
   TS
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 10 nM