Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3S)-2,2-dimethyl-3-phenyl-3-(1-pyridin-3-ylindazol-5-yl)-N-(1,3,4-thiadiazol-2-yl)propanamide
    Show/Hide
 PubChem ID
CID: 72192290
Canonical SMILES
CC(C)([C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1cccnc1)C(=O)Nc1nncs1
    Show/Hide
Compound Formula C25H22N6OS
Compound Structure
Protein Name
 Protein Info 
Glucocorticoid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 1
Uniprot ID
P04150
Gene Name
NR3C1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 19 nM
   TI
   LI
   LO
   TS
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 132 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 0.9 nM