Brief Information of the Compound and Protein
Compound Name
8-(dibenzo[b,d]thiophen-4-yl)-2-morpholino-4H-chromen-4-one
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PubChem ID
CID: 11327430
SID: 16417480
Canonical SMILES
O=c1cc(oc2c(cccc12)-c1cccc2c3ccccc3sc12)N1CCOCC1
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Compound Formula C25H19NO3S
Compound Structure
Protein Name
DNA-dependent protein kinase catalytic subunit
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Atypical protein kinase group
>
Atypical protein kinase PIKK family
Uniprot ID
P78527
Gene Name
PRKDC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  1
1
EC50 = 212 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 10 nM
2 IC50 = 12 nM
3 IC50 = 14 nM
4 IC50 = 20 nM
5 IC50 = 28 nM
6 IC50 = 30 nM
7 IC50 = 40 nM
8 IC50 = 42 nM
9 Ki = 0.65 nM