Brief Information of the Compound and Protein
Compound Name
1-ethyl-3-[4-[7-[(3S)-3-ethylmorpholin-4-yl]-1,3-dimethylpyrazolo[4,3-d]pyrimidin-5-yl]phenyl]urea
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PubChem ID
CID: 51355348
SID: 121274352
Canonical SMILES
CCNC(=O)Nc1ccc(cc1)-c1nc(N2CCOC[C@@H]2CC)c2n(C)nc(C)c2n1
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Compound Formula C22H29N7O2
Compound Structure
Protein Name
Serine/threonine-protein kinase mTOR
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Atypical protein kinase group
>
Atypical protein kinase PIKK family
>
Atypical protein kinase FRAP subfamily
Uniprot ID
P42345
Gene Name
MTOR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000048 PC-3 Homo sapiens (Human)  2
1
IC50 = 4 nM
   TI
   LI
   LO
   TS
2
IC50 = 8 nM
   TI
   LI
   LO
   TS