Brief Information of the Compound and Protein
Compound Name
6-[2-oxo-2-[3-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-2-yl]ethyl]pyridine-3-carbonitrile
    Show/Hide
PubChem ID
CID: 71813653
Canonical SMILES
FC(F)(F)c1c2CCCCn2nc1C(=O)Cc1ccc(cn1)C#N
    Show/Hide
Compound Formula C16H13F3N4O
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
P31424
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 7178 nM
   TI
   LI
   LO
   TS