Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-cyclopentyl-N-[(2S,3R)-3-hydroxy-1-phenyl-4-[[3-(trifluoromethyl)phenyl]methylamino]butan-2-yl]-6-oxo-5-(2-oxopyrrolidin-1-yl)pyridine-3-carboxamide
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 PubChem ID
CID: 71598543
Canonical SMILES
O[C@H](CNCc1cccc(c1)C(F)(F)F)[C@H](Cc1ccccc1)NC(=O)c1cc(N2CCCC2=O)c(=O)n(c1)C1CCCC1
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Compound Formula C33H37F3N4O4
Compound Structure
Protein Name
 Protein Info 
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 210 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 76 nM