Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2S)-2-[[[4-[2-(2-hydroxypropan-2-yl)-5-methylbenzimidazol-1-yl]cyclohexyl]amino]methyl]-2,3-dihydro-1H-indene-5-carbonitrile
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 PubChem ID
SID: 56250226
Canonical SMILES
Cc1ccc2n([C@@H]3CC[C@@H](CC3)NC[C@H]3Cc4ccc(cc4C3)C#N)c(nc2c1)C(C)(C)O
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Compound Formula C28H34N4O
Compound Structure
Protein Name
 Protein Info 
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 20 nM
   TI
   LI
   LO
   TS
2
IC50 = 8.7 nM
   TI
   LI
   LO
   TS