Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-Chloro-pyridine-2-carboxylic acid [3-((1SR,6RS)-3-amino-4-thia-2-aza-bicyclo[4.1.0]hept-2-en-1-yl)-phenyl]-amide
    Show/Hide
 PubChem ID
CID: 73353577
Canonical SMILES
NC1=NC2(c3cccc(NC(=O)c4ccc(Cl)cn4)c3)CC2CS1
    Show/Hide
Compound Formula C17H15ClN4OS
Compound Structure
Protein Name
 Protein Info 
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 140 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 760 nM