Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-N-(3-(4-Amino-6-methyl-5-azaspiro[2.5]oct-4-en-6-yl)-4-fluorophenyl)-5-chloropicolinamide
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 PubChem ID
CID: 71713954
Canonical SMILES
C[C@@]1(c2cc(NC(=O)c3ccc(Cl)cn3)ccc2F)CCC2(CC2)C(N)=N1
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Compound Formula C20H20ClFN4O
Compound Structure
Protein Name
 Protein Info 
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 15 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 31 nM