Brief Information of the Compound and Protein
Compound Name
(11aR)-9-(trifluoromethyl)-1,2,3,4,11,11a-hexahydropyrazino[1,2-b]isoquinolin-6-one
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PubChem ID
CID: 11361103
SID: 49848256
Canonical SMILES
FC(F)(F)c1ccc2C(=O)N3CCNC[C@H]3Cc2c1
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Compound Formula C13H13F3N2O
Compound Structure
Protein Name
5-hydroxytryptamine receptor 2B
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P41595
Gene Name
HTR2B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000065 HEK293-EBNA Homo sapiens (Human)  2
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
2
Ki = 778 nM
   TI
   LI
   LO
   TS