Brief Information of the Compound and Protein
Compound Name
(11aR)-6-oxo-1,2,3,4,11,11a-hexahydropyrazino[1,2-b]isoquinoline-9-carbonitrile
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PubChem ID
CID: 68691189
Canonical SMILES
O=C1N2CCNC[C@H]2Cc2cc(ccc12)C#N
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Compound Formula C13H13N3O
Compound Structure
Protein Name
5-hydroxytryptamine receptor 2C
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P28335
Gene Name
HTR2C
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000065 HEK293-EBNA Homo sapiens (Human)  2
1
EC50 = 610 nM
   TI
   LI
   LO
   TS
2
Ki = 5931 nM
   TI
   LI
   LO
   TS