Brief Information of the Compound and Protein
Compound Name
(11aR)-1,2,3,4,11,11a-hexahydropyrazino[1,2-b]isoquinolin-6-one
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PubChem ID
CID: 24826786
SID: 49848151
Canonical SMILES
O=C1N2CCNC[C@H]2Cc2ccccc12
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Compound Formula C12H14N2O
Compound Structure
Protein Name
5-hydroxytryptamine receptor 2C
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P28335
Gene Name
HTR2C
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000065 HEK293-EBNA Homo sapiens (Human)  2
1
EC50 = 36 nM
   TI
   LI
   LO
   TS
2
Ki = 24 nM
   TI
   LI
   LO
   TS