Brief Information of the Compound and Protein
Compound Name
5-chloro-6-methyl-N-(2-phenylethyl)-2-pyridin-2-ylpyrimidin-4-amine
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PubChem ID
CID: 2740174
SID: 17503678
Canonical SMILES
Cc1nc(nc(NCCc2ccccc2)c1Cl)-c1ccccn1
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Compound Formula C18H17ClN4
Compound Structure
Protein Name
Methionine aminopeptidase 2
Protein Classification
Enzyme
>
Protease
>
Metallo protease
>
Metallo protease MG clan
>
Metallo protease M24A subfamily
Uniprot ID
P50579
Gene Name
METAP2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000023 BTI-Tn-5B1-4 Trichoplusia ni (Cabbage looper)  1
1
IC50 = 9000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 7000 nM