Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-(4-methyl-1-methylsulfonylpiperidin-4-yl)-3,4,5,8,10-pentazatricyclo[7.3.0.02,6]dodeca-1,5,7,9,11-pentaene
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 PubChem ID
SID: 125006116
Canonical SMILES
CC1(CCN(CC1)S(C)(=O)=O)n1nnc2cnc3[nH]ccc3c12
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Compound Formula C14H18N6O2S
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase JAK1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
P23458
Gene Name
JAK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000128 TF-1
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 220 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 7.9 nM