Brief Information of the Compound and Protein
Compound Name
CHEMBL2392487
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Canonical SMILES
C(N1CCC(CC1)n1nnc2cnc3[nH]ccc3c12)c1ccccc1
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Compound Formula C19H20N6
Compound Structure
Protein Name
Tyrosine-protein kinase JAK1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
P23458
Gene Name
JAK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000128 TF-1 Homo sapiens (Human)  1
1
EC50 = 121 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 8.5 nM