Brief Information of the Compound and Protein
Compound Name
N-methyl-2-phenyl-N-((5R,7S,8S)-8-(pyrrolidin-1-yl)-1-oxaspiro[4.5]decan-7-yl)acetamide
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PubChem ID
CID: 73350518
Canonical SMILES
CN(C(=O)Cc1ccccc1)[C@H]1C[C@]2(CCCO2)CC[C@@H]1N1CCCC1
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Compound Formula C22H32N2O2
Compound Structure
Protein Name
Kappa-type opioid receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Opioid receptor
Uniprot ID
P41145
Gene Name
OPRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 16 nM
   TI
   LI
   LO
   TS
2
Ki = 6.4 nM
   TI
   LI
   LO
   TS