Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine
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 PubChem ID
CID: 3386
SID: 14874184
Canonical SMILES
CNCCC(Oc1ccc(cc1)C(F)(F)F)c1ccccc1
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Compound Formula C17H18F3NO
Compound Structure
Protein Name
 Protein Info 
Sodium-dependent dopamine transporter
Protein Classification
Transporter
>
Electrochemical transporter
>
SLC superfamily of solute carriers
>
SLC06 neurotransmitter transporter family
Uniprot ID
Q01959
Gene Name
SLC6A3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  7
1
IC50 = 4400 nM
   TI
   LI
   LO
   TS
2
IC50 = 6000 nM
   TI
   LI
   LO
   TS
3
IC50 = 9120.11 nM
   TI
   LI
   LO
   TS
4
IC50 = 18400 nM
   TI
   LI
   LO
   TS
5
IC50 = 19500 nM
   TI
   LI
   LO
   TS
6
Ki = 3764 nM
   TI
   LI
   LO
   TS
7
Ki = 6670 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Kd = 3600 nM
2 Ki = 1900 nM
3 Ki = 6000 nM