Brief Information of the Compound and Protein
Compound Name
(1R)-1-(3-cyclohexyl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaen-4-yl)ethane-1,2-diol
    Show/Hide
PubChem ID
CID: 71681692
Canonical SMILES
OC[C@H](O)c1nc2cnc3[nH]ccc3c2n1C1CCCCC1
    Show/Hide
Compound Formula C16H20N4O2
Compound Structure
Protein Name
Tyrosine-protein kinase JAK1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
P23458
Gene Name
JAK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000128 TF-1 Homo sapiens (Human)  1
1
EC50 = 320 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 7.2 nM