Brief Information of the Compound and Protein
Compound Name
 Compound Info 
CHEMBL2386628
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Canonical SMILES
CO[C@H]1CC[C@@H](CC1)n1c(nc2cnc3[nH]ccc3c12)[C@@H](C)O
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Compound Formula C17H22N4O2
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase JAK1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
P23458
Gene Name
JAK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000128 TF-1
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 240 nM
   TI
   LI
   LO
   TS
2
EC50 = 280 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 4.9 nM