Brief Information of the Compound and Protein
Compound Name
2-[3-fluoro-4-(methanesulfonamido)phenyl]-N-[[2-[(4-methoxyphenyl)methoxy]-6-(trifluoromethyl)pyridin-3-yl]methyl]propanamide
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PubChem ID
CID: 71698888
Canonical SMILES
COc1ccc(COc2nc(ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)C(F)(F)F)cc1
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Compound Formula C25H25F4N3O5S
Compound Structure
Protein Name
Transient receptor potential cation channel subfamily V member 1
Protein Classification
Ion channel
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Voltage-gated ion channel
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Transient receptor potential channel
Uniprot ID
Q8NER1
Gene Name
TRPV1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  2
1
IC50 = 653 nM
   TI
   LI
   LO
   TS
2
Ki = 2.6 nM
   TI
   LI
   LO
   TS