Brief Information of the Compound and Protein
Compound Name
3-[4-[2-[2-(cyanomethyl)phenyl]ethynyl]-2-fluorophenyl]propanoic acid
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PubChem ID
CID: 66553168
SID: 152159727
Canonical SMILES
OC(=O)CCc1ccc(cc1F)C#Cc1ccccc1CC#N
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Compound Formula C19H14FNO2
Compound Structure
Protein Name
Free fatty acid receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Free fatty acid receptor
Uniprot ID
O14842
Gene Name
FFAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000094 1321N1 Homo sapiens (Human)  1
1
EC50 = 5.888 nM
   TI
   LI
   LO
   TS
CL000460 Flp-In-T-REx-293 Homo sapiens (Human)  1
1
Ki = 85.11 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  3
1
EC50 = 18.62 nM
   TI
   LI
   LO
   TS
2
EC50 = 22.91 nM
   TI
   LI
   LO
   TS
3
EC50 = 26.3 nM
   TI
   LI
   LO
   TS