Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[2-(1H-indazol-4-yl)-6-[(4-methanesulfonylpiperazin-1-yl)methyl]thieno[3,2-d]pyrimidin-4-yl]morpholine
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 PubChem ID
CID: 17755052
SID: 29212926
Canonical SMILES
CS(=O)(=O)N1CCN(Cc2cc3nc(nc(N4CCOCC4)c3s2)-c2cccc3[nH]ncc23)CC1
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Compound Formula C23H27N7O3S2
Compound Structure
Protein Name
 Protein Info 
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P42338
Gene Name
PIK3CB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 17 nM
   TI
   LI
   LO
   TS
2
IC50 = 33 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3 nM
2 IC50 = 31 nM
3 IC50 = 32 nM
4 IC50 = 33 nM
5 IC50 = 181 nM
6 IC50 = 251.19 nM
7 IC50 = 324 nM
8 Kd = 2.1 nM
9 Kd = 16 nM