Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[(3R,5R)-3,5-dihydroxy-7-(hydroxyamino)-7-oxoheptyl]-5-(4-fluorophenyl)-N,4-diphenyl-2-propan-2-ylpyrrole-3-carboxamide
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 PubChem ID
CID: 71655138
Canonical SMILES
CC(C)c1c(C(=O)Nc2ccccc2)c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC(=O)NO)-c1ccccc1
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Compound Formula C33H36FN3O5
Compound Structure
Protein Name
 Protein Info 
3-hydroxy-3-methylglutaryl-coenzyme A reductase
Protein Classification
Enzyme
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Oxidoreductase
Uniprot ID
P04035
Gene Name
HMGCR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 9.2 nM
   TI
   LI
   LO
   TS
2
IC50 = 5700 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 12.3 nM