Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(1R,2R)-N-(4-(6-ethylpyridin-2-yl)-3-(2H-indazol-5-yl)isothiazol-5-yl)-2-methylcyclopropanecarboxamide hydrochloride
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 PubChem ID
CID: 71717643
Canonical SMILES
CCc1cccc(-c2c(-c3ccc4n[nH]cc4c3)nsc2NC(=O)[C@@H]2C[C@H]2C)n1.Cl
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Compound Formula C22H22ClN5OS
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 1
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
Q13255
Gene Name
GRM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000125 MCB3901
 Cell Line Info 
Mesocricetus auratus (Golden hamster)  1
1
IC50 = 3110 nM
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