Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(1R,2R)-N-[4-[6-(difluoromethyl)pyridin-2-yl]-3-(2-methylindazol-5-yl)-1,2-thiazol-5-yl]-2-methylcyclopropane-1-carboxamide
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 PubChem ID
CID: 67425408
SID: 163559569
Canonical SMILES
C[C@@H]1C[C@H]1C(=O)Nc1snc(c1-c1cccc(n1)C(F)F)-c1ccc2nn(C)cc2c1
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Compound Formula C22H19F2N5OS
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 1
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
Q13255
Gene Name
GRM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000125 MCB3901
 Cell Line Info 
Mesocricetus auratus (Golden hamster)  1
1
IC50 = 1020 nM
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