Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(1R,2R)-2-methyl-N-(3-(2-methyl-2H-indazol-5-yl)-4-(pyridin-2-yl)isothiazol-5-yl)cyclopropanecarboxamide hydrochloride
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 PubChem ID
CID: 67103556
SID: 163561583
Canonical SMILES
C[C@@H]1C[C@H]1C(=O)Nc1snc(-c2ccc3nn(C)cc3c2)c1-c1ccccn1.Cl
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Compound Formula C21H20ClN5OS
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000125 MCB3901
 Cell Line Info 
Mesocricetus auratus (Golden hamster)  1
1
IC50 = 29 nM
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