Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[(1R)-2-(4-chlorophenyl)-1-[4-oxo-6-(1H-pyrazol-4-yl)-3H-quinazolin-2-yl]ethyl]-2-pyridin-3-ylacetamide
    Show/Hide
 PubChem ID
CID: 136252256
SID: 163593643
Canonical SMILES
Clc1ccc(C[C@@H](NC(=O)Cc2cccnc2)c2nc3ccc(cc3c(=O)[nH]2)-c2cn[nH]c2)cc1
    Show/Hide
Compound Formula C26H21ClN6O2
Compound Structure
Protein Name
 Protein Info 
Rho-associated protein kinase 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase DMPK family
>
AGC protein kinase ROCK subfamily
Uniprot ID
O75116
Gene Name
ROCK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 239 nM
   TI
   LI
   LO
   TS