Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[(1S)-1-amino-2-(3-fluorophenyl)ethyl]-8-methoxy-6-(1H-pyrazol-4-yl)-3H-quinazolin-4-one
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 PubChem ID
CID: 136240978
SID: 163593918
Canonical SMILES
COc1cc(cc2c1nc([nH]c2=O)[C@@H](N)Cc1cccc(F)c1)-c1cn[nH]c1
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Compound Formula C20H18FN5O2
Compound Structure
Protein Name
 Protein Info 
Rho-associated protein kinase 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase DMPK family
>
AGC protein kinase ROCK subfamily
Uniprot ID
O75116
Gene Name
ROCK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 8 nM
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