Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-(1H-pyrazol-4-yl)-2-[(3S,4R)-4-[4-(trifluoromethyl)phenyl]pyrrolidin-3-yl]-3H-quinazolin-4-one
    Show/Hide
 PubChem ID
CID: 136252258
SID: 163594349
Canonical SMILES
FC(F)(F)c1ccc(cc1)[C@@H]1CNC[C@H]1c1nc2ccc(cc2c(=O)[nH]1)-c1cn[nH]c1
    Show/Hide
Compound Formula C22H18F3N5O
Compound Structure
Protein Name
 Protein Info 
Rho-associated protein kinase 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase DMPK family
>
AGC protein kinase ROCK subfamily
Uniprot ID
O75116
Gene Name
ROCK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 2 nM
   TI
   LI
   LO
   TS