Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-chloro-N-[(1S,3S)-3-[(4-methoxybenzoyl)amino]cyclohexyl]benzamide
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 PubChem ID
CID: 71717729
Canonical SMILES
COc1ccc(cc1)C(=O)N[C@H]1CCC[C@@H](C1)NC(=O)c1cccc(Cl)c1
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Compound Formula C21H23ClN2O3
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 266 nM
   TI
   LI
   LO
   TS
2
Ki = 674 nM
   TI
   LI
   LO
   TS