Brief Information of the Compound and Protein
Compound Name
1-[3,5-bis(trifluoromethyl)phenyl]-3-[4-(1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)phenyl]urea
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PubChem ID
CID: 71575640
SID: 163619552
Canonical SMILES
FC(F)(F)c1cc(NC(=O)Nc2ccc(Oc3ncnc4n[nH]cc34)cc2)cc(c1)C(F)(F)F
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Compound Formula C20H12F6N6O2
Compound Structure
Protein Name
Receptor-type tyrosine-protein kinase FLT3
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase PDGFR family
Uniprot ID
P36888
Gene Name
FLT3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000091 MV4-11 Homo sapiens (Human)  1
1
IC50 = 17 nM
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