Brief Information of the Compound and Protein
Compound Name
N-[3-[(1S,7S)-3-amino-4-thia-2-azabicyclo[5.1.0]oct-2-en-1-yl]-4-fluorophenyl]-5-cyanopyridine-2-carboxamide
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PubChem ID
CID: 71183925
SID: 163462104
Canonical SMILES
NC1=N[C@]2(C[C@H]2CCS1)c1cc(NC(=O)c2ccc(cn2)C#N)ccc1F
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Compound Formula C19H16FN5OS
Compound Structure
Protein Name
Beta-secretase 2
Protein Classification
Enzyme
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Hydrolase
Uniprot ID
Q6IE75
Gene Name
BACE2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000416 INS-1E Rattus norvegicus (Rat)  1
1
IC50 = 5 nM
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