Brief Information of the Compound and Protein
Compound Name
rac-N-(3-(3-amino-4-thia-2-azabicyclo[5.1.0]oct-2-en-1-yl)-4-fluorophenyl)-5-cyanopicolinamide
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PubChem ID
CID: 71720622
Canonical SMILES
N#Cc1ccc(C(=O)Nc2ccc(F)c(C34CC3CCSC(N)=N4)c2)nc1
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Compound Formula C19H16FN5OS
Compound Structure
Protein Name
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
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Aspartic protease
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Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 52 nM
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