Brief Information of the Compound and Protein
Compound Name
Trans-8-ethyl-4-methyl-6-(trifluoromethyl)-2,3,3a,4-tetrahydro-1H-pyrrolo[3,4-c]isoquinolin-5(9bH)-one hydrochloride
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PubChem ID
CID: 11595190
SID: 16697827
Canonical SMILES
CCc1cc2c(c(C(F)(F)F)c1)C(=O)N(C)[C@H]1CNC[C@H]21.Cl
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Compound Formula C15H18ClF3N2O
Compound Structure
Protein Name
5-hydroxytryptamine receptor 2B
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P41595
Gene Name
HTR2B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000065 HEK293-EBNA Homo sapiens (Human)  2
1
EC50 = 268 nM
   TI
   LI
   LO
   TS
2
Ki = 140 nM
   TI
   LI
   LO
   TS