Brief Information of the Compound and Protein
Compound Name
(3aS,9bR)-6-(trifluoromethyl)-2,3,3a,4-tetrahydro-1H-pyrrolo[3,4-c]isoquinolin-5(9bH)-one hydrochloride
    Show/Hide
PubChem ID
CID: 71518890
SID: 163511018
Canonical SMILES
Cl.O=C1N[C@@H]2CNC[C@H]2c2cccc(C(F)(F)F)c21
    Show/Hide
Compound Formula C12H12ClF3N2O
Compound Structure
Protein Name
5-hydroxytryptamine receptor 2C
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P28335
Gene Name
HTR2C
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000065 HEK293-EBNA Homo sapiens (Human)  2
1
EC50 = 62 nM
   TI
   LI
   LO
   TS
2
Ki = 1052 nM
   TI
   LI
   LO
   TS